(Senior) Scientist CMC Operations

The company
Lava Therapeutics (LAVA) generates and develops next generation γδ T cell engaging bispecific antibodies for the treatment of cancer. LAVA started its operations in 2017 and is advancing its proprietary platform and pipeline of bispecific therapeutic antibodies, building on cutting-edge research originating from the VU University Medical Center / Cancer Center Amsterdam. The company is now located at the Science Park in Utrecht and at the Agrifood Plaza building in Den Bosch. Expanding our team with new, talented employees is key to LAVA’s future success. We are currently looking for a

(Senior) Scientist CMC Operations

The position
As (Senior) Scientist CMC Operations you are part of the CMC Development team. You work closely together with internal and external project teams and CMC management on the effective design, execution, and analysis of the experimental work to deliver the development program for LAVA drug candidates. The  execution of experiments will be mainly performed in a virtual environment by outsouring the experimental work to contract labs and CDMOs,. You assist in the technology transfer of processes/products to our CDMO’s while keeping a focus on the scientific understanding of our products and processes. You assist in the development of processes and analytical methods governing manufacture and testing of Drug Substance and Drug Product. You assemble and maintain the product development information repository to allow efficient retrieval of development reports, protocols, specifications and other relevant documentation. You design, manage, and interpret experiments for formulation and process development. You monitor and communicate progress on outsourced activities through project meetings and planning tools and you present data at CMC meetings and to management. You represent LAVA’s interest in external project meetings. You write and review development reports, regulatory documentation enabling clinical testing (e.g. CTD sections and responses to health authority questions) and you perform literature searches.

You have an MSc or PhD qualification in Biologics/Biotechnology with a minimum of 5-10 years of relevant work experience in Biotechnological process development with a focus on cell culture/fermentation. You are an excellent researcher with the ability to identify and define problems, develop hypotheses and develop and execute plans to solve these. You have a trackrecord of successful designing, execution and analysis of experiments with a strong statistical focus.
You have strong problem-solving and trouble-shooting skills and a proven ability to learn and act on dynamic information at a rapid pace. You take initiative, enjoy working in a team and inspire others with your enthusiasm. You pay attention to detail and self-reflect on the quality of your work. You are capable of working on several projects in parallel and prioritize appropriately. You are able to travel domestically and internationally. Finally, you have outstanding written and verbal communication skills in Dutch and English.

The offer
A full time position. A set of excellent labour conditions. A permanent position after one year of temporary contract and a positive appraisal. Salary and benefits according to biotech industry standards. The location of the position will be at LAVA’s office in Den Bosch for at least 60 % of the time.

Working at LAVA
LAVA Therapeutics offers an attractive set of labour conditions, recognizing and rewarding its talented and motivated employees. This includes the ability to work together with a group of highly experienced leaders and professionals, who all have a track-record of success in their field of business and in Life Science industry. We offer flexible working hours, a premium-free pension plan, 30 paid vacation days, opportunities for growth and development and a professional working environment, in which hard working is balanced with fun.

Our Core Values
Our company culture is built on five important Core Values: Innovation, Teamwork, Results-orientation, Flexibility and Fun. We understand that innovation is at the heart of what we do. We drive the ability to innovate and we all have a strong awareness about emerging scientific and business opportunities. We work closely as a team, have a constructive and collaborative mindset and we put the common interest of the company above our own individual interest. We have a strong orientation on results, we meet agreed goals in a timely and efficient manner and we deliver on our promises. We are flexible, adapt well to changing circumstances and work well under pressure. Finally, we all contribute to a safe, professional and enjoyable workplace in which people are treated respectfully and diversity is embraced.

How to apply
Please send your CV together with a cover letter to hr@lavatherapeutics.com referring to the Sr. Scientist CMC Operations vacancy.

For more information about this vacant position, you can contact Peter Machielsen (Sr. Director CMC Operations) at p.machielsen@lavatherapeutics.com.
Acquisition related to this vacancy is not appreciated.

Your application and related information will remain strictly confidential.